ZNF519P4

Across TCGA pan-cancer cohorts, ZNF519P4 RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated ZNF519P4 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher ZNF519P4 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated ZNF519P4 expression acts as an unfavorable survival marker, although some lineages such as SKCM and ESCA show a favorable association.

MESO, BRCA, and COAD are the cancer types where ZNF519P4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Tertile	III,IV	0.069	0.580	<.001	108	view →
BRCA	OS	Tertile	All	0.387	0.589	<.001	72	view →
COAD	OS	Tertile	IV	0.045	0.659	<.001	36	view →
ACC	DFS	Tertile	All	0.195	0.748	.003	21	view →
KICH	DFS	Tertile	III,IV	0.025	0.773	<.001	18	view →
STAD	DFS	Tertile	IV	0.083	0.379	.001	18	view →
PRAD	OS	Tertile	All	0.921	0.996	.012	12	view →
SKCM	DFS	Tertile	All	0.882	0.610	.011	12	view →
DLBC	OS	Tertile	All	0.613	0.945	.049	9	view →
ESCA	DFS	Tertile	III,IV	0.672	0.269	.041	6	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

ZNF519P4–MESO (OS)

Open the MESO breakdown →