ZNF518B

Across TCGA cell cohorts, ZNF518B mutation is significantly associated with the RNA expression of many other genes, with 114 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF518B-associated genes across cancer lineages are OR2L8, PPY, and SALL3. Each is linked with ZNF518B in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF518B-to-partner and partner-to-ZNF518B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR2L8 grouped by ZNF518B-low versus ZNF518B-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF518B→partner) and Y-score (partner→ZNF518B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	OR2L8 →	+0.017	+4.169	<.001	.008	3	2
OVARY	PPY →	+0.212	+4.029	<.001	.009	3	2
BLOOD_Myeloma	SALL3 →	+0.060	+4.807	<.001	.006	3	1
OESOPHAGUS	DEFB4B →	+0.200	+4.857	<.001	<.001	3	1
OESOPHAGUS	NOX3 →	+0.022	+4.392	<.001	.003	3	1
LARGE_INTESTINE	RNF167 →	+0.561	+3.212	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 114 associations by consensus.

OR2L8 by ZNF518B expression — CNS

Explore this box plot interactively →