ZNF516

Across TCGA patient cohorts, ZNF516 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,976 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ZNF516-associated proteins across cancer lineages are ZNF516_S852, ZNF516_S116, and RPRD1A. Each is linked with ZNF516 in more than 6 cancer types. Because this analysis shows association rather than direction, both ZNF516-to-partner and partner-to-ZNF516 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF516 versus ZNF516_S852 in BRCA, with a Pearson correlation of 0.64.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF516→partner) and Y-score (partner→ZNF516) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ZNF516_S852 →	+0.652	+1.182	<.001	<.001	3	7
BRCA	ZNF516_S116 →	+0.620	+1.007	<.001	<.001	3	6
HNSC	RPRD1A →	+0.337	+0.567	<.001	<.001	3	6
LUAD	ZNF516_T930 →	+0.987	+0.952	<.001	<.001	3	6
UCEC	HDGFL3 →	+0.753	+1.050	<.001	<.001	3	5
HNSC	TRRAP →	+0.198	+0.778	.002	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,976 associations by consensus.

ZNF516 vs ZNF516_S852 — BRCA

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