ZNF516

Across TCGA patient cohorts, ZNF516 protein abundance is significantly associated with the RNA expression of many other genes, with 11,117 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZNF516-associated genes across cancer lineages are ELP2, RPRD1A, and DYM. Each is linked with ZNF516 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZNF516-to-partner and partner-to-ZNF516 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF516 versus ELP2 in BRCA, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF516→partner) and Y-score (partner→ZNF516) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ELP2 →	+0.852	+0.609	<.001	<.001	3	4
HNSC	RPRD1A →	+0.639	+0.338	<.001	<.001	3	4
OV	DYM →	+0.497	+0.647	.004	.003	3	4
BRCA	TXNL4A →	+0.494	+0.455	<.001	.004	3	4
BRCA	HAUS1 →	+0.599	+0.496	<.001	<.001	3	4
LSCC	HDHD2 →	+0.541	+0.361	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,117 associations by consensus.

ZNF516 vs ELP2 — BRCA

Explore this scatter interactively →