ZNF516

Across TCGA patient cohorts, ZNF516 protein abundance is significantly associated with the protein abundance of many other proteins, with 18,678 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZNF516-associated proteins across cancer lineages are SFPQ, WDR33, and ZMYND8. Each is linked with ZNF516 in more than 6 cancer types. Because this analysis shows association rather than direction, both ZNF516-to-partner and partner-to-ZNF516 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF516 versus SFPQ in GBM, with a Pearson correlation of 0.43.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF516→partner) and Y-score (partner→ZNF516) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SFPQ →	+0.201	+0.339	<.001	<.001	3	7
GBM	WDR33 →	+0.254	+0.489	<.001	<.001	3	7
CCRCC	ZMYND8 →	+0.317	+0.719	<.001	<.001	3	6
LSCC	MEPCE →	+0.416	+0.334	<.001	.001	3	6
BRCA	ZNF516_S116 →	+0.824	+0.624	<.001	<.001	3	5
GBM	CDC73 →	+0.293	+0.434	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,678 associations by consensus.

ZNF516 vs SFPQ — GBM

Explore this scatter interactively →