ZNF516

Across TCGA cell cohorts, ZNF516 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,353 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ZNF516-associated GO terms across cancer lineages are Regulation of myoblast fusion, Peptidyl-serine modification, and Regulation of organelle assembly. Each is linked with ZNF516 in more than 11 cancer types. Because this analysis shows association rather than direction, both ZNF516-to-partner and partner-to-ZNF516 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of myoblast fusion grouped by ZNF516-low versus ZNF516-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF516→partner) and Y-score (partner→ZNF516) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Regulation of myoblast fusion →	+0.106	+1.461	<.001	.001	3	11
KIDNEY	Peptidyl-serine modification →	+0.088	+1.034	.001	.003	3	10
LUNG_SCLC	Regulation of organelle assembly →	+0.038	+1.633	<.001	<.001	3	10
STOMACH	Regulation of syncytium formation by plasma membrane fusion →	+0.101	+1.488	<.001	.001	1	12
KIDNEY	Peptidyl-serine phosphorylation →	+0.088	+1.034	.001	.003	3	10
LUNG_SCLC	Peptidyl-amino acid modification →	+0.036	+1.523	<.001	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,353 associations by consensus.

Regulation of myoblast fusion by ZNF516 expression — BREAST

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