ZNF514

Across TCGA cell cohorts, ZNF514 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,412 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF514-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Negative regulation of syncytium formation by plasma membrane fusion, and Spliceosomal complex assembly. Each is linked with ZNF514 in more than 16 cancer types. Because this analysis shows association rather than direction, both ZNF514-to-partner and partner-to-ZNF514 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by ZNF514-low versus ZNF514-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF514→partner) and Y-score (partner→ZNF514) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Negative regulation of myoblast fusion →	+0.108	+0.951	<.001	<.001	3	17
BREAST	Negative regulation of syncytium formation by plasma membrane fusion →	+0.114	+1.047	<.001	<.001	3	17
BREAST	Spliceosomal complex assembly →	+0.075	+0.791	<.001	.003	3	16
STOMACH	Regulation of syncytium formation by plasma membrane fusion →	+0.135	+1.068	<.001	<.001	3	16
STOMACH	Viral translational termination-reinitiation →	+0.087	+0.878	<.001	<.001	3	15
STOMACH	Regulation of myoblast fusion →	+0.135	+0.876	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,412 associations by consensus.

Negative regulation of myoblast fusion by ZNF514 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →