ZNF512

Across TCGA patient cohorts, ZNF512 mutation is significantly associated with the RNA expression of many other genes, with 3,176 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF512-associated genes across cancer lineages are VN1R36P, PHF7, and LACTB. Each is linked with ZNF512 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF512-to-partner and partner-to-ZNF512 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, VN1R36P grouped by ZNF512-low versus ZNF512-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF512→partner) and Y-score (partner→ZNF512) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	VN1R36P →	+0.171	+5.187	<.001	.007	3	2
UCEC	PHF7 →	+0.310	+2.959	.006	<.001	3	2
UCEC	LACTB →	+0.504	+2.093	<.001	<.001	3	2
UCEC	ENO2 →	+0.633	+2.513	.001	<.001	3	2
UCEC	NPRL2 →	+0.270	+1.828	.002	<.001	3	2
SKCM	ITGB1BP1 →	+0.507	+3.353	.008	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,176 associations by consensus.

VN1R36P by ZNF512 expression — STAD

Explore this box plot interactively →