ZNF512

Across TCGA patient cohorts, ZNF512 mutation is significantly associated with the total protein of many other genes, with 24 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF512-associated genes across cancer lineages are PDCD4, ATM, and ERK2. Each is linked with ZNF512 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF512-to-partner and partner-to-ZNF512 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PDCD4 grouped by ZNF512-low versus ZNF512-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF512→partner) and Y-score (partner→ZNF512) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PDCD4 →	-0.413	-1.430	.006	.022	3	2
UCEC	ATM →	-0.301	-1.716	.041	.003	3	2
UCEC	ERK2 →	+0.150	+1.584	.016	.017	3	1
UCEC	Gab2 →	+0.275	+1.222	.017	.035	3	1
UCEC	IGFBP2 →	-0.575	-1.222	.006	.035	3	1
UCEC	IRS1 →	+0.183	+1.807	.006	.025	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

PDCD4 by ZNF512 expression — UCEC

Explore this box plot interactively →