ZNF512

Across TCGA cell cohorts, ZNF512 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,861 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ZNF512-associated GO terms across cancer lineages are Constitutive heterochromatin formation, Negative regulation of myoblast fusion, and Sister chromatid segregation. Each is linked with ZNF512 in more than 12 cancer types. Because this analysis shows association rather than direction, both ZNF512-to-partner and partner-to-ZNF512 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Constitutive heterochromatin formation grouped by ZNF512-low versus ZNF512-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF512→partner) and Y-score (partner→ZNF512) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Constitutive heterochromatin formation →	+0.115	+1.353	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Negative regulation of myoblast fusion →	+0.121	+1.411	<.001	<.001	3	12
BONE	Sister chromatid segregation →	+0.134	+0.856	.007	.001	3	12
STOMACH	Microtubule polymerization or depolymerization →	+0.145	+1.733	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	DNA biosynthetic process →	+0.082	+1.250	<.001	<.001	3	11
URINARY_TRACT	COP9 signalosome assembly →	+0.125	+1.418	.002	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,861 associations by consensus.

Constitutive heterochromatin formation by ZNF512 expression — SOFT_TISSUE

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