ZNF512

Across TCGA cell cohorts, ZNF512 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible ZNF512-associated genes across cancer lineages are MYH1, MORC1, and OR1A2. Each is linked with ZNF512 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF512-to-partner and partner-to-ZNF512 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MYH1 grouped by ZNF512-low versus ZNF512-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF512→partner) and Y-score (partner→ZNF512) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	MYH1 →	+0.009	+4.078	<.001	.009	3	1
LUNG_NSCLC_LUAD	MORC1 →	+0.158	+4.343	<.001	.002	3	1
LUNG_NSCLC_LUAD	OR1A2 →	+0.014	+4.681	<.001	.003	3	1
LUNG_NSCLC_LUAD	GAGE10 →	+0.165	+3.866	.009	.006	3	1
LUNG_NSCLC_LUAD	GAGE12J →	+2.594	+4.093	<.001	.004	3	1
LUNG_NSCLC_LUAD	IL5RA →	+0.031	+4.215	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

MYH1 by ZNF512 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →