Across TCGA patient cohorts, ZNF511 mutation is significantly associated with the total protein of many other genes, with 10 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF511-associated genes across cancer lineages are MEK1, Annexin-1, and VHL. Each is linked with ZNF511 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF511-to-partner and partner-to-ZNF511 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF511→partner) and Y-score (partner→ZNF511) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MEK1 →	+0.392	+3.584	.026	.002	3	1
UCEC	Annexin-1 →	+0.507	+2.827	.046	.035	3	1
UCEC	VHL →	-1.259	-2.459	<.001	.020	3	1
UCEC	Caspase-7-cleavedD198 →	+0.601	+3.019	.036	.019	3	1
UCEC	INPP4B →	-0.447	-3.459	.004	.005	2	1
UCEC	NDRG1_pT346 →	-0.562	-2.459	.017	.020	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

Exploration

ZNF511 survival (RNA) · tumor vs normal (RNA) · all ZNF511 data types