ZNF510

Across TCGA cell cohorts, ZNF510 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,485 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF510-associated GO terms across cancer lineages are Regulation of microtubule cytoskeleton organization, Regulation of heterochromatin organization, and Protein monoubiquitination. Each is linked with ZNF510 in more than 15 cancer types. Because this analysis shows association rather than direction, both ZNF510-to-partner and partner-to-ZNF510 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of microtubule cytoskeleton organization grouped by ZNF510-low versus ZNF510-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF510→partner) and Y-score (partner→ZNF510) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Regulation of microtubule cytoskeleton organization →	+0.081	+0.751	<.001	<.001	3	16
LUNG_SCLC	Regulation of heterochromatin organization →	+0.124	+0.600	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Protein monoubiquitination →	+0.082	+0.637	.001	.006	3	15
UPPER_AERODIGESTIVE_TRACT	Heterochromatin organization →	+0.064	+0.781	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Positive regulation of double-strand break repair →	+0.075	+0.747	.002	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Heterochromatin formation →	+0.075	+0.734	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,485 associations by consensus.

Regulation of microtubule cytoskeleton organization by ZNF510 expression — LUNG_SCLC

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