ZNF510

Across TCGA cell cohorts, ZNF510 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible ZNF510-associated genes across cancer lineages are ZP4, OR6C4, and CRYGB. Each is linked with ZNF510 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF510-to-partner and partner-to-ZNF510 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZP4 grouped by ZNF510-low versus ZNF510-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF510→partner) and Y-score (partner→ZNF510) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	ZP4 →	+0.013	+5.643	<.001	.002	3	1
LUNG_SCLC	OR6C4 →	+0.023	+5.029	<.001	.006	3	1
LUNG_SCLC	CRYGB →	+0.083	+5.643	<.001	.002	3	1
SKIN	OR10A7 →	+0.023	+6.022	<.001	.001	3	1
SKIN	KRTAP6-1 →	+0.100	+6.022	<.001	.001	3	1
SKIN	RBMY1E →	+0.262	+4.977	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

ZP4 by ZNF510 expression — LUNG_SCLC

Explore this box plot interactively →