ZNF507

Across TCGA pan-cancer cohorts, ZNF507 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated ZNF507 data layer compared with 25 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in glioblastoma multiforme (GBM), where higher ZNF507 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated ZNF507 expression acts as an unfavorable survival marker, although some lineages such as GBM and LUAD show a favorable association.

GBM, LUAD, and PDAC are the cancer types where ZNF507 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
GBM	OS	Median	All	0.895	0.712	.028	3	view →
LUAD	OS	Quartile	All	0.987	0.346	.023	2	view →
PDAC	OS	Tertile	All	0.805	0.885	.049	1	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

ZNF507–GBM (OS)

Open the GBM breakdown →