ZNF507

Across TCGA patient cohorts, ZNF507 mutation is significantly associated with the RNA expression of many other genes, with 5,553 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF507-associated genes across cancer lineages are RN7SL134P, GOT1, and ERGIC3. Each is linked with ZNF507 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF507-to-partner and partner-to-ZNF507 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL134P grouped by ZNF507-low versus ZNF507-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF507→partner) and Y-score (partner→ZNF507) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RN7SL134P →	+0.197	+5.289	<.001	<.001	3	3
UCEC	GOT1 →	+0.476	+2.023	<.001	<.001	3	3
UCEC	ERGIC3 →	-0.281	-2.137	.003	<.001	3	3
UCEC	EN2 →	+0.824	+2.169	.002	<.001	3	3
UCEC	RAB40A →	-0.228	-1.584	.001	<.001	3	3
UCEC	UQCRH →	+0.649	+2.839	.002	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,553 associations by consensus.

RN7SL134P by ZNF507 expression — CESC

Explore this box plot interactively →