ZNF507

Across TCGA patient cohorts, ZNF507 mutation is significantly associated with the total protein of many other genes, with 54 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF507-associated genes across cancer lineages are ASNS, c-Kit, and eEF2. Each is linked with ZNF507 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZNF507-to-partner and partner-to-ZNF507 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASNS grouped by ZNF507-low versus ZNF507-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF507→partner) and Y-score (partner→ZNF507) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	ASNS →	+0.683	+3.330	<.001	.005	3	4
BLCA	c-Kit →	-0.358	-3.321	.015	.009	3	2
UCEC	eEF2 →	+0.302	+1.241	.004	.015	3	2
UCEC	FoxM1 →	+0.154	+1.241	.044	.015	3	2
UCEC	GAPDH →	+0.371	+1.584	.019	.017	3	2
UCEC	PDCD4 →	-0.660	-3.247	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 54 associations by consensus.

ASNS by ZNF507 expression — COAD

Explore this box plot interactively →