ZNF507

Across TCGA cell cohorts, ZNF507 mutation is significantly associated with the RNA expression of many other genes, with 327 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF507-associated genes across cancer lineages are GAGE10, KSR2, and CX3CR1. Each is linked with ZNF507 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF507-to-partner and partner-to-ZNF507 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GAGE10 grouped by ZNF507-low versus ZNF507-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF507→partner) and Y-score (partner→ZNF507) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	GAGE10 →	+0.264	+3.188	<.001	.004	3	2
BLOOD_Leukemia	KSR2 →	+0.295	+3.798	.005	.004	3	2
LARGE_INTESTINE	CX3CR1 →	+0.110	+3.252	.007	.009	3	2
SOFT_TISSUE	CCR8 →	+0.022	+5.369	<.001	.004	3	1
SOFT_TISSUE	GPR139 →	+0.022	+5.369	<.001	.004	3	1
LUNG_NSCLC_LUAD	FGF23 →	+0.088	+3.201	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 327 associations by consensus.

GAGE10 by ZNF507 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →