ZNF506

Across TCGA patient cohorts, ZNF506 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,013 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ZNF506-associated proteins across cancer lineages are LMNB2, NFIX, and PRKG1. Each is linked with ZNF506 in more than 6 cancer types. Because this analysis shows association rather than direction, both ZNF506-to-partner and partner-to-ZNF506 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF506 versus LMNB2 in PDAC, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF506→partner) and Y-score (partner→ZNF506) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	LMNB2 →	+0.383	+0.516	<.001	<.001	3	7
HNSC	NFIX →	+0.519	+0.782	<.001	<.001	3	6
CCRCC	PRKG1 →	+0.502	+0.279	<.001	<.001	3	5
PDAC	RING1 →	+0.277	+0.316	<.001	<.001	3	5
GBM	RIOK2_S337 →	-0.402	-0.506	.002	<.001	3	5
BRCA	FERMT2 →	+0.557	+0.576	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,013 associations by consensus.

ZNF506 vs LMNB2 — PDAC

Explore this scatter interactively →