ZNF506

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZNF506 protein abundance is significantly associated with the RNA expression of many other genes, with 3,553 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF506-associated genes across cancer lineages are TAZ, NENF, and DCTD. Each is linked with ZNF506 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF506-to-partner and partner-to-ZNF506 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF506 versus TAZ in UCEC, with a Pearson correlation of -0.87.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF506→partner) and Y-score (partner→ZNF506) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECTAZ →-0.911-2.192.007.00732
UCECNENF →-1.892-2.975.002<.00132
UCECDCTD →-1.512-2.192<.001.00732
UCECRAB25 →-2.193-3.320.004.00232
UCECCARS2 →-1.806-3.503<.001.00132
LUADCASP6 →-0.985-0.949.006.00632
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,553 associations by consensus.

ZNF506 vs TAZ — UCEC

Per-sample scatter of ZNF506 vs TAZ in UCEC (Pearson r = -0.87).

Explore this scatter interactively →

Exploration