ZNF506

Across TCGA patient cohorts, ZNF506 mutation is significantly associated with the RNA expression of many other genes, with 1,064 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF506-associated genes across cancer lineages are RNU6-330P, ZFAT-AS1, and MIR5707. Each is linked with ZNF506 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF506-to-partner and partner-to-ZNF506 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-330P grouped by ZNF506-low versus ZNF506-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF506→partner) and Y-score (partner→ZNF506) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RNU6-330P →	+0.529	+8.057	<.001	.005	3	2
BRCA	ZFAT-AS1 →	+0.333	+5.020	<.001	.009	3	2
SKCM	MIR5707 →	+0.317	+4.884	<.001	.004	3	2
READ	BACH1-IT3 →	+0.138	+6.257	<.001	.001	3	2
READ	RPL12P5 →	+0.135	+5.219	<.001	.006	3	2
UCEC	RNVU1-28 →	+0.720	+1.805	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,064 associations by consensus.

RNU6-330P by ZNF506 expression — BRCA

Explore this box plot interactively →