ZNF506

Across TCGA cell cohorts, ZNF506 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,880 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF506-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Positive regulation of signal transduction by p53 class mediator, and Regulation of myoblast fusion. Each is linked with ZNF506 in more than 9 cancer types. Because this analysis shows association rather than direction, both ZNF506-to-partner and partner-to-ZNF506 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by ZNF506-low versus ZNF506-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF506→partner) and Y-score (partner→ZNF506) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Negative regulation of myoblast fusion →	+0.076	+1.091	.002	<.001	2	10
UPPER_AERODIGESTIVE_TRACT	Positive regulation of signal transduction by p53 class mediator →	+0.088	+1.497	.001	<.001	3	8
KIDNEY	Regulation of myoblast fusion →	+0.075	+1.482	.005	.004	2	9
OVARY	Negative regulation of syncytium formation by plasma membrane fusion →	+0.071	+1.163	.003	<.001	2	9
UPPER_AERODIGESTIVE_TRACT	Co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway →	+0.125	+1.414	<.001	.006	3	7
SOFT_TISSUE	Vesicle coating →	+0.062	+1.429	.006	.002	2	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,880 associations by consensus.

Negative regulation of myoblast fusion by ZNF506 expression — OVARY

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