ZNF506

Across TCGA cell cohorts, ZNF506 mutation is significantly associated with the drug of many other genes, with 9 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF506-associated genes across cancer lineages are CP466722, CX-5461, and PRT062607. Each is linked with ZNF506 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF506-to-partner and partner-to-ZNF506 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CP466722 grouped by ZNF506-low versus ZNF506-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF506→partner) and Y-score (partner→ZNF506) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CP466722 →	+0.409	+2.652	.039	.045	3	2
LARGE_INTESTINE	CX-5461 →	+0.588	+2.652	.047	.045	3	1
LARGE_INTESTINE	PRT062607 →	+0.564	+2.769	.025	.040	2	1
LARGE_INTESTINE	GSK2256098C →	+0.350	+2.906	.022	.033	1	1
LARGE_INTESTINE	GSK2276186C →	+0.497	+2.649	.031	.046	1	1
LARGE_INTESTINE	GSK2110183B →	+0.760	+2.649	.011	.046	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

CP466722 by ZNF506 expression — LARGE_INTESTINE

Explore this box plot interactively →