ZNF503

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZNF503 mutation is significantly associated with the RNA expression of many other genes, with 267 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF503-associated genes across cancer lineages are SNRPGP16, MTATP6P21, and RHEBP1. Each is linked with ZNF503 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF503-to-partner and partner-to-ZNF503 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNRPGP16 grouped by ZNF503-low versus ZNF503-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF503→partner) and Y-score (partner→ZNF503) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUADSNRPGP16 →+0.223+7.930<.001.00832
UCECMTATP6P21 →+0.253+2.704.003.00432
UCECRHEBP1 →+0.132+2.607.007.00332
COADRNA5SP457 →+0.382+3.622.009.00232
BRCAPRAMEF26 →+0.024+9.057<.001.00331
SKCMMTND2P8 →+0.055+4.302<.001.00231
Each partner links to its Q-omics profile. Showing the 6 strongest of 267 associations by consensus.

SNRPGP16 by ZNF503 expression — LUAD

Box plot of SNRPGP16 in ZNF503-low vs ZNF503-high samples in LUAD.

Explore this box plot interactively →

Exploration