ZNF503

Across TCGA patient cohorts, ZNF503 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. LGG shows the largest number of these associations.

The most reproducible ZNF503-associated genes across cancer lineages are GMP, CD8+ Tcm, and pDC. Each is linked with ZNF503 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF503-to-partner and partner-to-ZNF503 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GMP grouped by ZNF503-low versus ZNF503-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF503→partner) and Y-score (partner→ZNF503) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	GMP →	+0.199	+3.169	<.001	.049	3	2
LGG	CD8+ Tcm →	+0.042	+6.380	<.001	.023	3	1
UCEC	pDC →	+0.078	+2.839	.002	.034	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

GMP by ZNF503 expression — STAD

Explore this box plot interactively →