Across TCGA patient cohorts, ZNF502 mutation is significantly associated with the total protein of many other genes, with 41 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF502-associated genes across cancer lineages are ATM, FoxM1, and ACC1. Each is linked with ZNF502 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF502-to-partner and partner-to-ZNF502 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF502→partner) and Y-score (partner→ZNF502) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.586	-2.308	<.001	.005	3	3
UCEC	FoxM1 →	+0.255	+2.000	.002	<.001	3	2
UCEC	ACC1 →	+0.245	+2.335	.037	.018	3	2
UCEC	Notch1 →	+0.208	+2.321	<.001	<.001	3	2
UCEC	p62 Lck ligand →	+0.417	+3.906	<.001	<.001	3	2
UCEC	p70-S6K_pT389 →	-0.134	-1.700	.030	.040	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 41 associations by consensus.

Exploration

ZNF502 survival (RNA) · tumor vs normal (RNA) · all ZNF502 data types