Across TCGA pan-cancer cohorts, ZNF501 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated ZNF501 data layer compared with 27 for mass-spec protein and 1 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher ZNF501 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated ZNF501 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

LUAD, HNSC, and UCEC are the cancer types where ZNF501 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	All	0.163	0.835	<.001	30	view →
HNSC	OS	Median	All	0.167	0.710	.005	6	view →
UCEC	DFS	Median	All	0.978	0.891	.034	4	view →
BLCA	OS	Median	III,IV	0.248	0.683	.042	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: ZNF501 tumor-vs-normal RNA expression · all ZNF501 data types