ZNF501

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZNF501 mutation is significantly associated with the total protein of many other genes, with 35 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF501-associated genes across cancer lineages are FASN, PCNA, and Caspase-7-cleavedD198. Each is linked with ZNF501 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF501-to-partner and partner-to-ZNF501 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF501→partner) and Y-score (partner→ZNF501) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECFASN →+0.336+1.700.013.04233
UCECPCNA →+0.259+2.502<.001.00132
UCECCaspase-7-cleavedD198 →+0.744+3.019<.001<.00132
UCECCyclin-B1 →+0.705+2.070<.001.00132
UCECDi-Ras3 →-0.178-2.459<.001<.00132
UCEC14-3-3_beta →-0.113-2.057.001.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 35 associations by consensus.

Exploration