ZNF500

Across TCGA patient cohorts, ZNF500 mutation is significantly associated with the total protein of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF500-associated genes across cancer lineages are ATM and AMPK_pT172. Each is linked with ZNF500 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF500-to-partner and partner-to-ZNF500 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATM grouped by ZNF500-low versus ZNF500-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF500→partner) and Y-score (partner→ZNF500) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.555	-3.156	.011	.018	3	1
UCEC	AMPK_pT172 →	+0.393	+3.000	.048	.036	2	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

ATM by ZNF500 expression — UCEC

Explore this box plot interactively →