ZNF500

Across TCGA cell cohorts, ZNF500 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,861 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ZNF500-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Negative regulation of syncytium formation by plasma membrane fusion, and Negative regulation of autophagy. Each is linked with ZNF500 in more than 17 cancer types. Because this analysis shows association rather than direction, both ZNF500-to-partner and partner-to-ZNF500 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by ZNF500-low versus ZNF500-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF500→partner) and Y-score (partner→ZNF500) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Negative regulation of myoblast fusion →	+0.133	+0.707	<.001	.007	3	18
STOMACH	Negative regulation of syncytium formation by plasma membrane fusion →	+0.128	+0.513	<.001	.005	3	18
UPPER_AERODIGESTIVE_TRACT	Negative regulation of autophagy →	+0.083	+1.128	<.001	.001	3	17
OESOPHAGUS	Calcium-independent cell-matrix adhesion →	+0.260	+1.177	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Nuclear export →	+0.100	+1.259	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Regulation of TOR signaling →	+0.056	+1.269	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,861 associations by consensus.

Negative regulation of myoblast fusion by ZNF500 expression — STOMACH

Explore this box plot interactively →