ZNF497

Across TCGA patient cohorts, ZNF497 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,365 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF497-associated proteins across cancer lineages are RFX1, RRBP1, and ZSCAN18. Each is linked with ZNF497 in more than 4 cancer types. Because this analysis shows association rather than direction, both ZNF497-to-partner and partner-to-ZNF497 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF497 versus RFX1 in BRCA, with a Pearson correlation of 0.28.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF497→partner) and Y-score (partner→ZNF497) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RFX1 →	+0.196	+0.521	<.001	.001	3	5
BRCA	RRBP1 →	-0.310	-0.313	<.001	.004	3	5
HNSC	ZSCAN18 →	+0.648	+0.581	<.001	.007	3	5
GBM	TRIM24 →	+0.390	+0.507	.001	<.001	3	4
GBM	PRKRIP1 →	+0.393	+0.532	<.001	<.001	3	4
UCEC	RUVBL2 →	+0.271	+0.577	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,365 associations by consensus.

ZNF497 vs RFX1 — BRCA

Explore this scatter interactively →