ZNF497

Across TCGA patient cohorts, ZNF497 mutation is significantly associated with the RNA expression of many other genes, with 2,762 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF497-associated genes across cancer lineages are RNU6-580P, MIR325, and MIR1207. Each is linked with ZNF497 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF497-to-partner and partner-to-ZNF497 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-580P grouped by ZNF497-low versus ZNF497-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF497→partner) and Y-score (partner→ZNF497) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU6-580P →	+0.706	+4.251	<.001	.008	3	2
COAD	MIR325 →	+0.368	+5.409	<.001	.001	3	2
COAD	MIR1207 →	+0.995	+3.636	<.001	.006	3	2
COAD	OR2A5 →	+0.179	+3.843	<.001	.004	3	2
COAD	RPL35AP30 →	+0.326	+3.541	<.001	.007	3	2
COAD	EIF4EBP2P1 →	+0.533	+4.721	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,762 associations by consensus.

RNU6-580P by ZNF497 expression — COAD

Explore this box plot interactively →