ZNF497

Across TCGA cell cohorts, ZNF497 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,309 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF497-associated GO terms across cancer lineages are Negative regulation of DNA-templated transcription, elongation, Cilium movement involved in cell motility, and Sperm motility. Each is linked with ZNF497 in more than 16 cancer types. Because this analysis shows association rather than direction, both ZNF497-to-partner and partner-to-ZNF497 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of DNA-templated transcription, elongation grouped by ZNF497-low versus ZNF497-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF497→partner) and Y-score (partner→ZNF497) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Negative regulation of DNA-templated transcription, elongation →	+0.112	+0.868	<.001	<.001	3	17
URINARY_TRACT	Cilium movement involved in cell motility →	-0.125	-0.962	<.001	<.001	3	16
URINARY_TRACT	Sperm motility →	-0.136	-0.722	<.001	<.001	3	16
STOMACH	Regulation of nucleotide-excision repair →	+0.159	+0.978	.004	.001	3	16
URINARY_TRACT	Flagellated sperm motility →	-0.136	-0.722	<.001	<.001	3	16
BREAST	Negative regulation of mRNA splicing, via spliceosome →	+0.113	+0.752	<.001	.002	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,309 associations by consensus.

Negative regulation of DNA-templated transcription, elongation by ZNF497 expression — SOFT_TISSUE

Explore this box plot interactively →