ZNF496

Across TCGA cell cohorts, ZNF496 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,668 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF496-associated GO terms across cancer lineages are Positive regulation of gene expression, epigenetic, Transcription initiation-coupled chromatin remodeling, and DNA-templated transcription initiation. Each is linked with ZNF496 in more than 16 cancer types. Because this analysis shows association rather than direction, both ZNF496-to-partner and partner-to-ZNF496 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of gene expression, epigenetic grouped by ZNF496-low versus ZNF496-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF496→partner) and Y-score (partner→ZNF496) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Positive regulation of gene expression, epigenetic →	+0.129	+1.033	.002	.003	3	16
BONE	Transcription initiation-coupled chromatin remodeling →	+0.085	+0.804	<.001	.001	3	16
UPPER_AERODIGESTIVE_TRACT	DNA-templated transcription initiation →	+0.070	+0.979	.005	.001	3	16
BONE	Negative regulation of gene expression, epigenetic →	+0.097	+0.746	<.001	.004	2	17
STOMACH	Heterochromatin organization →	+0.078	+1.018	<.001	<.001	3	16
BONE	Heterochromatin formation →	+0.091	+0.701	.001	.004	2	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,668 associations by consensus.

Positive regulation of gene expression, epigenetic by ZNF496 expression — LIVER

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