Across TCGA patient cohorts, ZNF493 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,108 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF493-associated proteins across cancer lineages are PSIP1, YME1L1, and RPL7. Each is linked with ZNF493 in more than 4 cancer types. Because this analysis shows association rather than direction, both ZNF493-to-partner and partner-to-ZNF493 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF493→partner) and Y-score (partner→ZNF493) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PSIP1 →	+0.458	+0.429	<.001	<.001	3	5
PDAC	YME1L1 →	-0.381	-0.639	<.001	<.001	3	5
GBM	RPL7 →	-0.456	-0.489	<.001	.001	3	5
GBM	RPS8 →	-0.337	-0.632	<.001	<.001	3	5
PDAC	LMNB2 →	+0.359	+0.473	<.001	<.001	3	5
HNSC	MAP1S →	+0.298	+0.924	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,108 associations by consensus.

Exploration

ZNF493 survival (RNA) · tumor vs normal (RNA) · all ZNF493 data types