Across TCGA cell cohorts, ZNF493 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,197 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ZNF493-associated GO terms across cancer lineages are Protein polyubiquitination, Positive regulation of double-strand break repair, and Regulation of alternative mRNA splicing, via spliceosome. Each is linked with ZNF493 in more than 12 cancer types. Because this analysis shows association rather than direction, both ZNF493-to-partner and partner-to-ZNF493 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF493→partner) and Y-score (partner→ZNF493) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Protein polyubiquitination →	+0.050	+1.153	<.001	.002	3	13
BREAST	Positive regulation of double-strand break repair →	+0.083	+1.598	<.001	<.001	3	13
LUNG_SCLC	Regulation of alternative mRNA splicing, via spliceosome →	+0.103	+1.671	<.001	<.001	3	13
OVARY	Hormone metabolic process →	-0.113	-1.046	<.001	<.001	3	12
LUNG_SCLC	Regulation of double-strand break repair →	+0.067	+1.219	.002	.005	3	12
OVARY	Spliceosomal complex assembly →	+0.086	+1.095	.001	.006	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,197 associations by consensus.

Exploration

ZNF493 survival (RNA) · tumor vs normal (RNA) · all ZNF493 data types