Across TCGA cell cohorts, ZNF493 mutation is significantly associated with the RNA expression of many other genes, with 94 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF493-associated genes across cancer lineages are F11, ST8SIA2, and ASB10. Each is linked with ZNF493 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF493-to-partner and partner-to-ZNF493 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF493→partner) and Y-score (partner→ZNF493) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	F11 →	+0.037	+2.560	<.001	.008	3	2
PANCREAS	ST8SIA2 →	+0.049	+4.035	<.001	.003	3	1
PANCREAS	ASB10 →	+0.010	+4.029	<.001	.007	3	1
PANCREAS	GABRG1 →	+0.016	+3.786	.001	.004	3	1
BLOOD_Leukemia	LUZP4 →	+0.485	+5.060	<.001	.001	3	1
BLOOD_Leukemia	IFNG →	+0.220	+4.152	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 94 associations by consensus.

Exploration

ZNF493 survival (RNA) · tumor vs normal (RNA) · all ZNF493 data types