ZNF492

Across TCGA patient cohorts, ZNF492 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,132 significant associations in total. STAD shows the largest number of these associations.

The most reproducible ZNF492-associated GO terms across cancer lineages are Nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, Nuclear-transcribed mRNA catabolic process, and Positive regulation of mRNA metabolic process. Each is linked with ZNF492 in more than 26 cancer types. Because this analysis shows association rather than direction, both ZNF492-to-partner and partner-to-ZNF492 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay grouped by ZNF492-low versus ZNF492-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF492→partner) and Y-score (partner→ZNF492) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay →	+0.095	+0.450	<.001	<.001	3	27
ESCA	Nuclear-transcribed mRNA catabolic process →	+0.093	+0.438	<.001	<.001	3	26
STAD	Positive regulation of mRNA metabolic process →	+0.068	+0.257	<.001	<.001	3	26
ESCA	RNA localization →	+0.090	+0.340	<.001	<.001	3	26
ESCA	Nucleobase-containing compound transport →	+0.076	+0.494	<.001	<.001	3	26
ESCA	Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay →	+0.085	+0.441	<.001	<.001	3	26

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,132 associations by consensus.

Nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay by ZNF492 expression — ESCA

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