ZNF491

Across TCGA cell cohorts, ZNF491 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,261 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF491-associated GO terms across cancer lineages are Intraciliary retrograde transport, Tubulin deacetylation, and Cilium or flagellum-dependent cell motility. Each is linked with ZNF491 in more than 11 cancer types. Because this analysis shows association rather than direction, both ZNF491-to-partner and partner-to-ZNF491 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Intraciliary retrograde transport grouped by ZNF491-low versus ZNF491-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF491→partner) and Y-score (partner→ZNF491) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Intraciliary retrograde transport →	+0.063	+0.559	<.001	<.001	3	12
STOMACH	Tubulin deacetylation →	+0.136	+0.823	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Cilium or flagellum-dependent cell motility →	-0.080	-0.144	.001	.009	3	10
BONE	Peptidyl-lysine acetylation →	+0.144	+1.232	<.001	.001	3	10
UPPER_AERODIGESTIVE_TRACT	Cilium-dependent cell motility →	-0.080	-0.144	.001	.009	3	10
UPPER_AERODIGESTIVE_TRACT	Cilium movement involved in cell motility →	-0.081	-0.144	.001	.009	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,261 associations by consensus.

Intraciliary retrograde transport by ZNF491 expression — BREAST

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