Across TCGA patient cohorts, ZNF490 protein abundance is significantly associated with the RNA expression of many other genes, with 258 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ZNF490-associated genes across cancer lineages are MICALL1, RIMS4, and MTMR8. Each is linked with ZNF490 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF490-to-partner and partner-to-ZNF490 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF490→partner) and Y-score (partner→ZNF490) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MICALL1 →	-1.382	-0.733	.001	.003	3	1
BRCA	RIMS4 →	+2.348	+0.681	.004	.009	3	1
BRCA	MTMR8 →	-0.592	-0.681	.002	.009	3	1
BRCA	SCML2 →	-1.683	-0.823	<.001	<.001	3	1
BRCA	ARHGEF7 →	-0.891	-0.731	<.001	.004	3	1
BRCA	NME3 →	+1.656	+0.788	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 258 associations by consensus.

Exploration

ZNF490 survival (RNA) · tumor vs normal (RNA) · all ZNF490 data types