Across TCGA patient cohorts, ZNF490 mutation is significantly associated with the RNA expression of many other genes, with 1,161 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF490-associated genes across cancer lineages are RPL23AP82, RNU6-728P, and TRDJ2. Each is linked with ZNF490 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF490-to-partner and partner-to-ZNF490 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF490→partner) and Y-score (partner→ZNF490) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RPL23AP82 →	+0.423	+2.524	<.001	<.001	3	2
UCEC	RNU6-728P →	+0.103	+2.750	.001	.003	3	2
UCEC	TRDJ2 →	+0.610	+1.699	.001	.001	3	2
UCEC	IGHD5-12 →	+0.304	+2.538	<.001	.005	3	2
COAD	UBBP3 →	+0.627	+3.875	.001	.004	3	2
UCEC	MIR3690 →	+0.282	+2.146	.002	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,161 associations by consensus.

Exploration

ZNF490 survival (RNA) · tumor vs normal (RNA) · all ZNF490 data types