Across TCGA cell cohorts, ZNF490 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,141 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF490-associated GO terms across cancer lineages are Positive regulation of T-helper 17 cell lineage commitment, Response to starvation, and Post-Golgi vesicle-mediated transport. Each is linked with ZNF490 in more than 13 cancer types. Because this analysis shows association rather than direction, both ZNF490-to-partner and partner-to-ZNF490 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF490→partner) and Y-score (partner→ZNF490) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Positive regulation of T-helper 17 cell lineage commitment →	+0.168	+0.429	<.001	<.001	3	14
OESOPHAGUS	Response to starvation →	+0.045	+0.263	.001	.008	3	13
OESOPHAGUS	Post-Golgi vesicle-mediated transport →	+0.052	+0.307	.009	.001	3	13
SKIN	Endosomal transport →	+0.063	+0.454	<.001	<.001	3	13
BLOOD_Lymphoma	Protein polyubiquitination →	+0.046	+0.715	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Regulation of intracellular steroid hormone receptor signaling pathway →	+0.070	+0.343	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,141 associations by consensus.

Exploration

ZNF490 survival (RNA) · tumor vs normal (RNA) · all ZNF490 data types