ZNF488

Across TCGA patient cohorts, ZNF488 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,918 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF488-associated proteins across cancer lineages are ORC6_T195, ARCN1, and FERMT1. Each is linked with ZNF488 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZNF488-to-partner and partner-to-ZNF488 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF488 versus ORC6_T195 in LSCC, with a Pearson correlation of 0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF488→partner) and Y-score (partner→ZNF488) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ORC6_T195 →	+0.858	+0.939	.001	<.001	3	4
BRCA	ARCN1 →	-0.316	-0.708	<.001	<.001	3	4
OV	FERMT1 →	+1.015	+0.822	<.001	<.001	3	4
BRCA	PDXDC1 →	-0.409	-0.544	<.001	<.001	3	4
CCRCC	BAIAP2L1 →	+0.399	+0.099	.001	.001	3	3
BRCA	UCHL1 →	+0.846	+0.564	.003	.008	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,918 associations by consensus.

ZNF488 vs ORC6_T195 — LSCC

Explore this scatter interactively →