ZNF488

Across TCGA cell cohorts, ZNF488 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,290 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible ZNF488-associated GO terms across cancer lineages are Regulation of cardiac muscle tissue development, Protein depolymerization, and mRNA transport. Each is linked with ZNF488 in more than 9 cancer types. Because this analysis shows association rather than direction, both ZNF488-to-partner and partner-to-ZNF488 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of cardiac muscle tissue development grouped by ZNF488-low versus ZNF488-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF488→partner) and Y-score (partner→ZNF488) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Regulation of cardiac muscle tissue development →	+1.454	+1.239	.003	.003	2	10
BREAST	Protein depolymerization →	+0.093	+1.510	<.001	<.001	3	8
BREAST	mRNA transport →	+0.114	+1.611	<.001	<.001	3	7
BREAST	mRNA export from nucleus →	+0.102	+1.242	<.001	<.001	3	7
LIVER	Regulation of mitochondrion organization →	+0.068	+0.965	<.001	.006	3	7
BREAST	Blood coagulation, fibrin clot formation →	+0.333	+1.198	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,290 associations by consensus.

Regulation of cardiac muscle tissue development by ZNF488 expression — LIVER

Explore this box plot interactively →