ZNF486

Across TCGA patient cohorts, ZNF486 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,282 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF486-associated proteins across cancer lineages are NFIX_S265, GLIS2_S159, and HIP1. Each is linked with ZNF486 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZNF486-to-partner and partner-to-ZNF486 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF486 versus NFIX_S265 in LUAD, with a Pearson correlation of 0.29.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF486→partner) and Y-score (partner→ZNF486) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	NFIX_S265 →	+0.397	+1.132	.002	.005	3	4
PDAC	GLIS2_S159 →	+0.587	+0.754	<.001	<.001	3	4
LUAD	HIP1 →	+0.232	+1.231	.005	<.001	3	4
BRCA	UTRN →	+0.259	+1.273	.002	<.001	3	4
HNSC	RPL10A →	-0.207	-0.865	<.001	<.001	3	4
LSCC	NCOA7 →	+0.248	+0.821	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,282 associations by consensus.

ZNF486 vs NFIX_S265 — LUAD

Explore this scatter interactively →