ZNF486

Across TCGA patient cohorts, ZNF486 protein abundance is significantly associated with the RNA expression of many other genes, with 364 significant associations in total. COAD shows the largest number of these associations.

The most reproducible ZNF486-associated genes across cancer lineages are TRIOBP, MCAT, and PIGH. Each is linked with ZNF486 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF486-to-partner and partner-to-ZNF486 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF486 versus TRIOBP in COAD, with a Pearson correlation of 0.78.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF486→partner) and Y-score (partner→ZNF486) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	TRIOBP →	+0.802	+2.935	.001	.005	3	1
COAD	MCAT →	+0.602	+2.812	.006	.006	3	1
COAD	PIGH →	+0.523	+2.159	.005	.008	3	1
COAD	VTI1B →	+0.591	+2.160	.003	.008	3	1
COAD	AHSA1 →	+0.644	+2.416	.002	.001	3	1
COAD	PSMB5 →	+0.664	+2.416	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 364 associations by consensus.

ZNF486 vs TRIOBP — COAD

Explore this scatter interactively →