ZNF486

Across TCGA cell cohorts, ZNF486 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,673 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ZNF486-associated GO terms across cancer lineages are Glycoside metabolic process, snRNA processing, and Actin nucleation. Each is linked with ZNF486 in more than 5 cancer types. Because this analysis shows association rather than direction, both ZNF486-to-partner and partner-to-ZNF486 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Glycoside metabolic process grouped by ZNF486-low versus ZNF486-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF486→partner) and Y-score (partner→ZNF486) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Glycoside metabolic process →	-0.253	-1.526	.006	.003	3	6
BONE	snRNA processing →	+0.076	+1.862	.003	<.001	3	6
BLOOD_Lymphoma	Actin nucleation →	+0.072	+1.129	<.001	<.001	3	6
SOFT_TISSUE	Spliceosomal tri-snRNP complex assembly →	+0.070	+1.229	.001	<.001	3	6
OESOPHAGUS	Termination of RNA polymerase II transcription →	+0.085	+0.706	.001	.005	3	5
BLOOD_Myeloma	Regulation of peptidyl-threonine phosphorylation →	-0.172	-1.156	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,673 associations by consensus.

Glycoside metabolic process by ZNF486 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →