Across TCGA cell cohorts, ZNF485 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible ZNF485-associated genes across cancer lineages are C6orf118, MMP26, and CBLL2. Each is linked with ZNF485 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF485-to-partner and partner-to-ZNF485 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF485→partner) and Y-score (partner→ZNF485) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	C6orf118 →	+0.122	+3.115	<.001	.004	3	1
LARGE_INTESTINE	MMP26 →	+0.027	+3.217	.002	.006	3	1
OVARY	CBLL2 →	+0.036	+5.196	<.001	.005	3	1
OVARY	OR4D2 →	+0.016	+5.196	<.001	.005	3	1
LUNG_NSCLC_LUAD	OR1L6 →	+0.014	+4.662	<.001	.005	3	1
LUNG_NSCLC_LUAD	CETN1 →	+0.010	+5.266	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

Exploration

ZNF485 survival (RNA) · tumor vs normal (RNA) · all ZNF485 data types