ZNF484

Across TCGA patient cohorts, ZNF484 protein abundance is significantly associated with the RNA expression of many other genes, with 10,683 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ZNF484-associated genes across cancer lineages are GPR171, ZNF516, and RUNDC3A. Each is linked with ZNF484 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF484-to-partner and partner-to-ZNF484 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF484 versus GPR171 in LUAD, with a Pearson correlation of -0.87.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF484→partner) and Y-score (partner→ZNF484) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	GPR171 →	-1.738	-0.548	<.001	.009	3	2
LUAD	ZNF516 →	+1.667	+0.815	.009	.002	3	1
LUAD	RUNDC3A →	-0.470	-0.521	.005	.006	3	1
LUAD	PLPPR1 →	-2.217	-0.840	.003	<.001	3	1
LUAD	C2orf50 →	+1.755	+0.814	.002	.004	3	1
LUAD	CXCL1 →	+3.020	+0.618	.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,683 associations by consensus.

ZNF484 vs GPR171 — LUAD

Explore this scatter interactively →