ZNF484

Across TCGA cell cohorts, ZNF484 mutation is significantly associated with the RNA expression of many other genes, with 16 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF484-associated genes across cancer lineages are KRT25, OR12D2, and CCDC54. Each is linked with ZNF484 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF484-to-partner and partner-to-ZNF484 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRT25 grouped by ZNF484-low versus ZNF484-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF484→partner) and Y-score (partner→ZNF484) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	KRT25 →	+0.053	+5.087	<.001	.004	3	1
URINARY_TRACT	OR12D2 →	+0.136	+5.087	<.001	.004	3	1
LARGE_INTESTINE	CCDC54 →	+0.155	+3.736	<.001	.004	3	1
LARGE_INTESTINE	G6PC2 →	+0.036	+3.658	<.001	.005	3	1
LARGE_INTESTINE	CLEC4F →	+0.290	+3.974	<.001	.002	3	1
LARGE_INTESTINE	FCRL4 →	+0.019	+3.510	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

KRT25 by ZNF484 expression — URINARY_TRACT

Explore this box plot interactively →